Article
Deep transcriptomic profiling of Dahl salt-sensitive rat kidneys with mutant form of Resp18.
Biochemical and biophysical research communications - 1 Oct 2021
Ashraf Usman M, Mell Blair, Jose Pedro A, Kumarasamy Sivarajan
Abstract excerpt
Expression of Regulated endocrine specific protein 18 (Resp18) is localized in numerous tissues and cell types; however, its exact cellular function is unknown. We previously showed that targeted disruption of the Resp18 locus in the Dahl SS (SS) rat (Resp18mutant) results in higher blood pressure (BP), increased renal fibrosis, increased urinary protein excretion, and decreased mean survival time following a...
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