Article
Epigenetic Modifications in T Cells: The Role of DNA Methylation in Salt-Sensitive Hypertension.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2020
Dasinger John Henry, Alsheikh Ammar J, Abais-Battad Justine M, Pan Xiaoqing, Fehrenbach Daniel J, Lund Hayley, Roberts Michelle L, Cowley Allen W, Kidambi Srividya, Kotchen Theodore A, Liu Pengyuan, Liang Mingyu, Mattson David L
Abstract excerpt
The SS (Dahl salt sensitive) rat is an established model of hypertension and renal damage that is accompanied with immune system activation in response to a high-salt diet. Investigations into the effects of sodium-independent and dependent components of the diet were shown to affect the disease phenotype with SS/MCW (JrHsdMcwi) rats maintained on a purified diet (AIN-76A) presenting with a more severe phenotype...
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