Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct QTLs cosegregate with worse hypertension and renal disease in ovariectomized F2[Dahl S × R]-intercross rats.

Journal of hypertension - 1 Aug 2012

Herrera Victoria L, Matsubara Yuichi, Ponce Lorenz R, Ruiz-Opazo Nelson

Abstract excerpt

OBJECTIVES: Salt-sensitive hypertension is highly prevalent in postmenopausal women, with approximately 75% of postmenopausal women found to be hypertensive in the US. Insight from surgical menopause (ovariectomized) patients directly links the loss of endogenous estrogens to salt-sensitive hypertension in previously healthy, salt-resistant women. However, controversial benefit of hormone replacement therapy in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hypertension
Share to Kidney Diseases
Share to Myocardium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organ Size

Share to Ovariectomy

Share to Postmenopause

Share to Rats, Inbred Dahl

Share to Salt Tolerance

Source

Identifiers

PMID: 22688265
DOI: 10.1097/HJH.0b013e3283550eb8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct QTLs cosegregate with worse hypertension and renal disease in ovariectomized F2[Dahl S × R]-intercross rats.PMID 22688265Read ↗

Differential genetic basis for pre-menopausal and post-menopausal salt-sensitive hypertension.Semantic proximity Read ↗

Sex-specific QTLs and interacting loci underlie salt-sensitive hypertension and target organ complications in Dahl S/jrHS hypertensive rats.Semantic proximity Read ↗

Genomic map of cardiovascular phenotypes of hypertension in female Dahl S rats.Semantic proximity Read ↗

Ovarian Hormones Moderate Systolic Hypertension in Female <i>Eln</i> Haploinsufficient MiceSemantic proximity Read ↗

Estrogen-regulated renal progenitors determine pregnancy adaptation and preeclampsiaSemantic proximity Read ↗

Cardiac pathways distinguish two epistatic modules enacting BP quantitative trait loci and candidate gene analysis.Semantic proximity Read ↗

Geno-transcriptomic dissection of proteinuria in the uninephrectomized rat uncovers a molecular complexity with sexual dimorphism.Semantic proximity Read ↗

Dissecting the comprehensive relationship between blood pressure and bone mass: the observational association and pleiotropic drug targetsSemantic proximity Read ↗

Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats.Semantic proximity Read ↗

Conserved mammalian modularity of quantitative trait loci revealed human functional orthologs in blood pressure control.Semantic proximity Read ↗

Gender-specific genetic determinants of blood pressure and organ weight: pharmacogenetic approach.Semantic proximity Read ↗

Genetic linkage of albuminuria and renal injury in Dahl salt-sensitive rats on a high-salt diet: comparison with spontaneously hypertensive rats.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.