Article
RNA polymerase III control elements are required for trans-activation by the murine retroviral long terminal repeat sequences.
Biochemical and biophysical research communications - 2 Jan 2015
Hwang Yong-Woo, Yoo Na Kyung, Yang Heung Mo, Choi Sang-Yun
Abstract excerpt
RNA leukemia viruses induce T-cell lymphoblastic lymphomas or myeloid leukemias. Infection of cells with Moloney murine leukemia virus (M-MuLV) up-regulates the expression of a number of cellular genes, including those involved in T-lymphocyte activation. Previously, we demonstrated that this up-regulation occurs via the trans-activation activity of the M-MuLV long terminal repeat (LTR) sequences which produce an...
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