Article
Mutations that abrogate transactivational activity of the feline leukemia virus long terminal repeat do not affect virus replication.
Virology - 10 May 2003
Abujamra Ana L, Faller Douglas V, Ghosh Sajal K
Abstract excerpt
The U3 region of the LTR of oncogenic Moloney murine leukemia virus (Mo-MuLV) and feline leukemia viruses (FeLV) have been previously reported to activate expression of specific cellular genes in trans, such as MHC class I, collagenase IV, and MCP-1, in an integration-independent manner. It has been suggested that transactivation of these specific cellular genes by leukemia virus U3-LTR may contribute to the...
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