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Article

Human immunodeficiency virus type-1 transcription: role of the 5'-untranslated leader region (review).

1 May 1998

Abstract excerpt

Human immunodeficiency virus type-1 (HIV-1) transcription is dependent on the interaction of host-cell transcription factors with cis-regulatory DNA elements within the viral long terminal repeat (LTR). Much attention has focused on the series of sequence elements upstream of the transcriptional initiation site in the U3 region of the LTR including the Sp1 and NF-kappaB binding sites. Recent studies, however,...

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Identifiers

PMID: 9852310
DOI: 10.3892/ijmm.1.5.875

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