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Article

ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer.

Journal of virology - 1 Apr 2007

Mertz Jennifer A, Kobayashi Ryuji, Dudley Jaquelin P

Abstract excerpt

Type B leukemogenic virus (TBLV), a mouse mammary tumor virus (MMTV) variant, often induces T-cell leukemias and lymphomas by c-myc activation following viral DNA integration. Transfection assays using a c-myc reporter plasmid indicated that the TBLV long terminal repeat (LTR) enhancer is necessary for T-cell-specific increases in basal reporter activity. The sequence requirements for this effect were studied...

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Share to Binding Sites
Share to Core Binding Factor Alpha 2 Subunit
Share to Enhancer Elements, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nuclear Proteins

Share to Proto-Oncogene Proteins c-myb

Share to Retroviridae

Share to RNA-Binding Proteins

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Source

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Identifiers

PMID: 17229714
DOI: 10.1128/JVI.02253-06
PMCID: PMC1866045

Genes

RUNX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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