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Article

Alignment of U3 region sequences of mammalian type C viruses: identification of highly conserved motifs and implications for enhancer design.

Journal of virology - 1 Feb 1990

Golemis E A, Speck N A, Hopkins N

Abstract excerpt

We aligned published sequences for the U3 region of 35 type C mammalian retroviruses. The alignment reveals that certain sequence motifs within the U3 region are strikingly conserved. A number of these motifs correspond to previously identified sites. In particular, we found that the enhancer region of most of the viruses examined contains a binding site for leukemia virus factor b, a viral corelike element, the...

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Identifiers

PMID: 2153223
DOI: 10.1128/JVI.64.2.534-542.1990
PMCID: PMC249141

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