Article
Function of Rta is essential for lytic replication of murine gammaherpesvirus 68.
Journal of virology - 1 Oct 2001
Wu T T, Tong L, Rickabaugh T, Speck S, Sun R
Abstract excerpt
Rta, encoded primarily by open reading frame 50, is well conserved among gammaherpesviruses. It has been shown that the Rta proteins of Epstein Barr virus (EBV), Kaposi's sarcoma-associated herpesvirus (KSHV, or HHV-8), and murine gammaherpesvirus 68 (MHV-68; also referred to as gamma HV68) play an important role in viral reactivation from latency. However, the role of Rta during productive de novo infection has...
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