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Article

cis-Elements involved in expression of unspliced RNA in Moloney murine leukemia virus.

Biochemical and biophysical research communications - 25 Jan 2002

Hoshi Sakuo, Odawara Takashi, Oshima Masamichi, Kitamura Yoshihiro, Takizawa Hajime, Yoshikura Hiroshi

Abstract excerpt

Murine leukemia virus (MLV) produces the unspliced RNA and the singly spliced RNA at a proper ratio at a time. To identify cis-elements involved in the production of the unspliced RNA, we examined the level of unspliced RNA in a series of mutants derived from a prototype Moloney MLV mutant gag-encoding G3.6. Our present data indicated that nt 1560-1906 region in the CA-encoding region in gag was the negative...

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PMID: 11798195
DOI: 10.1006/bbrc.2001.6326

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