Article
Identification and characterization of an enhancer in the coding region of the genome of human immunodeficiency virus type 1.
1 Jun 1990
Abstract excerpt
Transcription of human immunodeficiency virus type 1 (HIV-1) is regulated by cis-acting DNA elements located in the viral long terminal repeats, by viral transregulatory proteins, and by cellular transcription factors acting in concert to modulate the degree of viral expression. We demonstrate that a DNA fragment corresponding to the central portion of the HIV-1 genome exhibits enhancer activity when cloned...
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