Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription.

Journal of molecular biology - 8 Mar 2002

Morin Pierre, Bragança José, Bandu Marie-Thérèse, Lin Rongtuan, Hiscott John, Doly Janine, Civas Ahmet

Abstract excerpt

Transcription of the murine interferon-A4 (IFN-A4) gene is mediated by a virus responsive element (VRE-A4) located in the promoter proximal [-120 to -43] region. VRE-A4 contains four DNA modules (A to D) which cooperate for maximal IFN-A4 activation following virus infection. The differential expression between the highly expressed IFN-A4 and the weakly inducible IFN-A11 gene promoters is essentially due to point...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Deoxyribonuclease I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Footprinting

Share to Electrophoretic Mobility Shift Assay

Share to Interferon-alpha

Share to Interferon Regulatory Factor-3

Share to Response Elements

Share to Transcription, Genetic

Source

Identifiers

PMID: 11884139
DOI: 10.1006/jmbi.2001.5401

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Preferential binding sites for interferon regulatory factors 3 and 7 involved in interferon-A gene transcription.PMID 11884139Read ↗

Recruitment of Multiple Interferon Regulatory Factors and Histone Acetyltransferase to the Transcriptionally Active Interferon A PromotersSemantic proximity Read ↗

Differential Regulation of Human Interferon A Gene Expression by Interferon Regulatory Factors 3 and 7Semantic proximity Read ↗

Distinct and Essential Roles of Transcription Factors IRF-3 and IRF-7 in Response to Viruses for IFN-α/β Gene InductionSemantic proximity Read ↗

Promoter organization of the interferon-A genes differentially affects virus-induced expression and responsiveness to TBK1 and IKKepsilon.Semantic proximity Read ↗

DNA-binding landscape of IRF3, IRF5 and IRF7 dimers: implications for dimer-specific gene regulationSemantic proximity Read ↗

Global and Distinct Targets of IRF-5 and IRF-7 during Innate Response to Viral InfectionSemantic proximity Read ↗

Selective DNA Binding and Association with the CREB Binding Protein Coactivator Contribute to Differential Activation of Alpha/Beta Interferon Genes by Interferon Regulatory Factors 3 and 7Semantic proximity Read ↗

Essential role of interferon regulatory factor 3 in direct activation of RANTES chemokine transcription.Semantic proximity Read ↗

Transcription Factor Redundancy Ensures Induction of the Antiviral StateSemantic proximity Read ↗

The control of interferon-inducible gene expression.Semantic proximity Read ↗

RNA polymerase III control elements are required for trans-activation by the murine retroviral long terminal repeat sequences.Semantic proximity Read ↗

A novel interferon-inducible domain: structural and functional analysis of the human interferon regulatory factor 1 gene promoter.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.