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Article

Effect of impaired renal function on the maintenance dose of warfarin in Japanese patients.

Journal of cardiology - 1 Mar 2015

Ichihara Naoaki, Ishigami Tomoaki, Umemura Satoshi

Abstract excerpt

BACKGROUND: Chronic kidney disease (CKD) alters dose-effect relationship not only of drugs eliminated by the kidney but also of some drugs metabolized by the liver and not renally excreted. It is not known whether impaired renal function alters dose-effect relationship of warfarin in Asian patients. It is also unknown whether the maintenance dose of warfarin can be predicted more accurately by incorporating renal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25442049
DOI: 10.1016/j.jjcc.2014.08.008

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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