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Article

Warfarin dosing in patients with impaired kidney function.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Nov 2010

Limdi Nita A, Limdi Mohit A, Cavallari Larisa, Anderson Aaron M, Crowley Michael R, Baird Melissa F, Allon Michael, Beasley T Mark

Abstract excerpt

BACKGROUND: In patients with kidney impairment, warfarin, a drug metabolized primarily by the cytochrome P-450 system, is initiated at similar doses and managed similarly as in the general medical population. Unfortunately, few data exist to guide dose adjustment in patients with decreased kidney function. Here, we determine the degree of warfarin dose reduction associated with kidney impairment and make...

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Share to Anticoagulants
Share to Cytochrome P-450 CYP2C9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glomerular Filtration Rate

Share to Mixed Function Oxygenases

Share to Renal Insufficiency

Share to Thrombophilia

Share to Vitamin K Epoxide Reductases

Share to Warfarin

Source

Open in PubMed Open full text

Identifiers

PMID: 20709439
DOI: 10.1053/j.ajkd.2010.05.023
PMCID: PMC2963672

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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