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Article

Acute kidney injury interacts with VKORC1 genotype on initiative warfarin dose among heart surgery recipients: a real-world research.

Scientific reports - 8 Dec 2023

Xiong Liang, Yu Feng, Ge Weihong, Xu Hang

Abstract excerpt

Patients who receive heart valve surgery need anticoagulation prophylaxis to reduce the risk of thrombosis. Warfarin often is a choice but its dosage varies due to gene and clinical factors. We aim to study, among them, if there is an interaction between acute kidney injury and two gene polymorphisms from this study. We extracted data of heart valve surgery recipients from the electronic health record (EHR)...

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Share to Aryl Hydrocarbon Hydroxylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiac Surgical Procedures

Share to Cytochrome P-450 CYP2C9

Share to Dose-Response Relationship, Drug

Share to Vitamin K Epoxide Reductases

Share to Warfarin

Source

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Identifiers

PMID: 38066032
DOI: 10.1038/s41598-023-46895-2
PMCID: PMC10709552

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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