CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects.

doi:10.1111/j.1365-2710.2011.01317.x

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Article

CYP4F2 gene polymorphism as a contributor to warfarin maintenance dose in Japanese subjects.

Journal of clinical pharmacy and therapeutics - 1 Aug 2012

Nakamura K, Obayashi K, Araki T, Aomori T, Fujita Y, Okada Y, Kurabayashi M, Hasegawa A, Ohmori S, Nakamura T, Yamamoto K

Abstract excerpt

WHAT IS KNOWN AND OBJECTIVE: Polymorphisms in the gene encoding CYP4F2 may partly explain the variability in warfarin maintenance dose by altering the metabolism of vitamin K. To determine the genetic factors that cause large inter-patient variability in warfarin efficacy, we investigated the relationship between serum warfarin concentration and CYP4F2 V433M (1347C>T, rs2108622) polymorphism in Japanese subjects....

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PMID: 22172097
DOI: 10.1111/j.1365-2710.2011.01317.x

Genes

VKORC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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