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Article

Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis.

The pharmacogenomics journal - 1 Aug 2015

Julià A, Ferrándiz C, Dauden E, Fonseca E, Fernández-López E, Sanchez-Carazo J L, Vanaclocha F, Puig L, Moreno-Ramírez D, Lopez-Estebaranz J L, Herrera E, de la Cueva P, Ávila G, Alonso A, Tortosa R, López-Lasanta M, Marsal S

Abstract excerpt

Psoriasis is a prevalent autoimmune disease of the skin that causes significant psychological and physical disability. Tumor necrosis factor (TNF)-blocking agents have proven to be highly efficacious in the management of moderate-to-severe psoriasis. However, a significant percentage of patients do not respond to this treatment. Recently, variation at the PDE3A-SLCO1C1 (phosphodiesterase 3A-SoLute Carrier Organic...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25403996
DOI: 10.1038/tpj.2014.71

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Association of the PDE3A-SLCO1C1 locus with the response to anti-TNF agents in psoriasis.PMID 25403996Read ↗

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