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Influence of Genetic Polymorphisms on Response to Biologics in Moderate-to-Severe Psoriasis

12 Apr 2021

Abstract excerpt

Psoriasis is a chronic inflammatory skin pathology of autoimmune origin and unknown etiology. There are various therapies for treating it, including a wide range of biopharmaceuticals indicated in moderate-to-severe psoriasis. Depending on their therapeutic target, they are classified as tumor necrosis factor inhibitors (anti-TNF) or cytokine inhibitors (interleukin-12, 23, and 17 antagonists). Although they have...

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PMID: 33921427
DOI: 10.3390/jpm11040293

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