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Article

TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis.

The Journal of investigative dermatology - 1 Mar 2012

Tejasvi Trilokraj, Stuart Philip E, Chandran Vinod, Voorhees John J, Gladman Dafna D, Rahman Proton, Elder James T, Nair Rajan P

Abstract excerpt

The tumor necrosis factor-alpha-induced protein 3 (TNFAIP3) gene has been associated with psoriasis, rheumatoid arthritis, type 1 diabetes mellitus, systemic lupus erythematosus, and celiac disease. TNFAIP3 encodes A20, a tumor necrosis factor (TNF)-α-inducible zinc finger protein thought to limit NF-κB-mediated immune responses. In this study, we report association of response of psoriasis to TNF blockers with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 22113471
DOI: 10.1038/jid.2011.376
PMCID: PMC3278539

Genes

TNF
TNFAIP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis.PMID 22113471Read ↗

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