The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity.

doi:10.1111/ced.12536

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity.

Clinical and experimental dermatology - 1 Jun 2015

Zhang C, Zhu K-J, Liu H, Quan C, Liu Z, Li S-J, Zhu C-Y, Li K-S, Fan Y-M

Abstract excerpt

BACKGROUND: Genome-wide association studies in white and Chinese Han populations have found that the single-nucleotide polymorphism (SNP) rs610604, at the tumour necrosis factor (TNF)-α-induced protein 3 (TNFAIP3) locus, is associated with psoriasis, and is also associated with response to TNF blockade in psoriasis. AIM: To examine whether this SNP is also associated with the clinical traits of psoriasis vulgaris...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Asian People

Share to DNA-Binding Proteins

Share to Intracellular Signaling Peptides and Proteins

Share to Nuclear Proteins

Share to Psoriasis

Share to Severity of Illness Index

Share to Tumor Necrosis Factor alpha-Induced Protein 3

Source

Open in PubMed

Identifiers

PMID: 25496073
DOI: 10.1111/ced.12536

Genes

TNFAIP3
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The TNFAIP3 polymorphism rs610604 both associates with the risk of psoriasis vulgaris and affects the clinical severity.PMID 25496073Read ↗

Association of rs610604 in TNFAIP3 and rs17728338 in TNIP1 gene polymorphisms with psoriasis susceptibility: a meta-analysis of case-control studies.Semantic proximity Read ↗

Association of rs610604 in TNFAIP3 and rs17728338 in TNIP1 gene polymorphisms with psoriasis susceptibility: A meta-analysis of case-control studiesSemantic proximity Read ↗

Meta-analysis of the TNFAIP3 region in psoriasis reveals a risk haplotype that is distinct from other autoimmune diseases.Semantic proximity Read ↗

Variants at HLA-A, HLA-C, and HLA-DQB1 Confer Risk of Psoriasis Vulgaris in Japanese.Semantic proximity Read ↗

Genetic liability to psoriasis predicts severe disease outcomesSemantic proximity Read ↗

TNFAIP3 gene polymorphisms are associated with response to TNF blockade in psoriasis.Semantic proximity Read ↗

IL36G genetic variant is independently associated with susceptibility, severity and joint involvement in psoriasis.Semantic proximity Read ↗

Single nucleotide polymorphisms in the tumor necrosis factor-alpha gene promoter region alter the risk of psoriasis vulgaris and psoriatic arthritis: a meta-analysis.Semantic proximity Read ↗

NLRP3 (rs10754558) gene polymorphism and tumor necrosis factor alpha as predictors for disease activity and response to methotrexate and adalimumab in psoriasis.Semantic proximity Read ↗

Association of NLRP1 and NLRP3 Polymorphisms with Psoriasis Vulgaris Risk in the Chinese Han Population.Semantic proximity Read ↗

TNFAIP3 and TNIP1 polymorphisms confer psoriasis risk in South Indian Tamils.Semantic proximity Read ↗

IL36G genetic variant is independently associated with susceptibility, severity and joint involvement in psoriasisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.