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Article

Impact of pharmacogenomics upon the therapeutic response to etanercept in psoriasis and psoriatic arthritis.

Expert opinion on drug safety - 1 Oct 2017

Murdaca Giuseppe, Negrini Simone, Magnani Ottavia, Penza Elena, Pellecchio Marco, Puppo Francesco

Abstract excerpt

INTRODUCTION: TNF-α inhibitors have demonstrated efficacy both as monotherapy and in combination with disease-modifying anti-rheumatic drugs (DMARDs) in the treatment of chronic inflammatory immune-mediated diseases. Etanercept is a decoy receptor" for TNF-α and it is composed of two p75 TNF-α receptors fused to human IgG1. Areas covered: We discuss the potential role of pharmacogenetics in predicting the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28750567
DOI: 10.1080/14740338.2017.1361404

Genes

TNF
TNFAIP3

Variants

rs1799724

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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