Article
New polymorphisms associated with response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis.
The pharmacogenomics journal - 1 Jan 2018
Prieto-Pérez R, Solano-López G, Cabaleiro T, Román M, Ochoa D, Talegón M, Baniandrés O, López-Estebaranz J L, de la Cueva P, Daudén E, Abad-Santos F
Abstract excerpt
Anti-tumor necrosis factor (anti-TNF) drugs are effective against psoriasis, although 20-30% of patients are nonresponders. Few pharmacogenomic studies have been performed to predict the response to anti-TNF drugs in psoriasis. We studied 173 polymorphisms to establish an association with the response to anti-TNF drugs in patients with moderate-to-severe plaque psoriasis (N=144). We evaluated the response using...
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