Article
Complex role of TNF variants in psoriatic arthritis and treatment response to anti-TNF therapy: evidence and concepts.
The Journal of investigative dermatology - 1 Oct 2014
Hüffmeier Ulrike, Mössner Rotraut
Abstract excerpt
Psoriatic arthritis (PsA) is a chronic inflammatory disease affecting joints, and it may manifest as peripheral arthritis, dactylitis, enthesitis, spondylitis, or sacroiliitis. In the great majority of patients, PsA is accompanied by the most frequent psoriatic manifestation--psoriasis vulgaris. The major genetic risk factor for PsA is an HLA-C allele, and in recent genome-wide association studies few other...
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