Article
GWAS replication study confirms the association of PDE3A-SLCO1C1 with anti-TNF therapy response in rheumatoid arthritis.
Pharmacogenomics - 1 May 2013
Acosta-Colman Isabel, Palau Núria, Tornero Jesús, Fernández-Nebro Antonio, Blanco Francisco, González-Alvaro Isidoro, Cañete Juan D, Maymó Joan, Ballina Javier, Fernández-Gutiérrez Benjamín, Olivé Alex, Corominas Héctor, Erra Alba, Canela-Xandri Oriol, Alonso Arnald, López Lasanta Maria, Tortosa Raül, Julià Antonio, Marsal Sara
Abstract excerpt
AIM: The present study was undertaken to replicate the association of candidate genes for anti-TNF response in rheumatoid arthritis. Candidate genes were selected from a recent genome-wide association study on anti-TNF response performed in a population from Denmark. MATERIALS & METHODS: Genomic DNA was obtained from 315 Spanish rheumatoid arthritis patients having received an anti-TNF agent as their first...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
