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Article

Tyms double (2R) and triple repeat (3R) confers risk for human oral squamous cell carcinoma.

Molecular biology reports - 1 Dec 2014

Bezerra Alexandre Medeiros, Sant'Ana Thalita Araújo, Gomes Adriana Vieira, de Lacerda Vidal Aurora Karla, Muniz Maria Tereza Cartaxo

Abstract excerpt

The oral cancer is responsible for approximately 3 % of cases of cancer in Brazil. Epidemiological studies have associated low folate intake with an increased risk of epithelial cancers, including oral cancer. Folic acid has a key role in DNA synthesis, repair, methylation and this is the basis of explanations for a putative role for folic acid in cancer prevention. The role of folic acid in carcinogenesis may be...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 25341694
DOI: 10.1007/s11033-014-3494-x

Genes

TYMS
MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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