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Article

Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.

Molecular biology reports - 1 Jan 2012

Galbiatti Ana Lívia Silva, Ruiz Mariangela Torreglosa, Rodrigues Juliana Olsen, Raposo Luiz Sérgio, Maníglia José Victor, Pavarino Érika Cristina, Goloni-Bertollo Eny Maria

Abstract excerpt

Functional polymorphisms in genes encoding enzymes involved in folate metabolism might modulate head and neck carcinoma risk because folate participates in DNA methylation and synthesis. We therefore conducted a case-control study of 853 individuals (322 head and neck cancer cases and 531 non-cancer controls) to investigate associations among MTHFR C677T and MTHFR A1298C polymorphisms and head and neck squamous...

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Source

Identifiers

PMID: 21556759
DOI: 10.1007/s11033-011-0781-7

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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