Article
The association between two polymorphisms in the TYMS gene and breast cancer risk: a meta-analysis.
Breast cancer research and treatment - 1 Jul 2011
Wang Jun, Wang Baocheng, Bi Jingwang, Di Jianshi
Abstract excerpt
Thymidylate synthase (TYMS), which catalyzes the conversion of deoxyuridine monophosphate to deoxythymidine monophosphate, is a central enzyme in the folate metabolic pathway. Epidemiological studies have evaluated the association between TYMS gene polymorphisms and breast cancer susceptibility; however, the published data are still inconclusive. To derive a more precise assessment of this relationship, we...
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