5-Methyltetrahydrofolate-homocysteine methyltransferase gene polymorphism (MTR) and risk of head and neck cancer.

doi:10.1590/s0100-879x2010007500034

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Article

5-Methyltetrahydrofolate-homocysteine methyltransferase gene polymorphism (MTR) and risk of head and neck cancer.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 May 2010

Galbiatti A L S, Ruiz M T, Biselli-Chicote P M, Chicote-Biselli P M, Raposo L S, Maniglia J V, Pavarino-Bertelli E C, Goloni-Bertollo E M

Abstract excerpt

The functional effect of the A>G transition at position 2756 on the MTR gene (5-methyltetrahydrofolate-homocysteine methyltransferase), involved in folate metabolism, may be a risk factor for head and neck squamous cell carcinoma (HNSCC). The frequency of MTR A2756G (rs1805087) polymorphism was compared between HNSCC patients and individuals without history of neoplasias. The association of this polymorphism with...

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PMID: 20490431
DOI: 10.1590/s0100-879x2010007500034

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rs1805087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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