Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.

Brazilian journal of otorhinolaryngology - 1 Jan 2000

Rodrigues Juliana Olsen, Galbiatti Ana Lívia Silva, Ruiz Mariangela Torreglosa, Raposo Luiz Sergio, Maniglia José Victor, Pavarino-Bertelli Erika Cristina, Goloni-Bertollo Eny Maria

Abstract excerpt

UNLABELLED: Methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism may be a risk factor for head and neck squamous cell carcinoma due to changes in folate levels that can induce disorders in the methylation pathway, which results in carcinogenesis. AIM: To evaluate MTHFR C677T polymorphism in patients with head and neck squamous cell carcinoma and in individuals with no history of cancer, and to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age Factors
Share to Aged

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Genetic Predisposition to Disease

Share to Polymerase Chain Reaction

Share to Polymorphism, Genetic

Share to Risk Factors

Share to Sex Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 21180947
PMCID: PMC9443740

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.PMID 21180947Read ↗

Polymorphisms and haplotypes in methylenetetrahydrofolate reductase gene and head and neck squamous cell carcinoma risk.Semantic proximity Read ↗

5-Methyltetrahydrofolate-homocysteine methyltransferase gene polymorphism (MTR) and risk of head and neck cancer.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase polymorphisms and risk of squamous cell carcinoma of the head and neck: a case-control analysis.Semantic proximity Read ↗

Head and neck cancer: genetic polymorphisms and folate metabolism.Semantic proximity Read ↗

MTHFR C677T and A1298C polymorphisms as predictors of radiotherapy response in head and neck squamous cell carcinoma.Semantic proximity Read ↗

Association between 11 genetic polymorphisms in folate-metabolising genes and head and neck cancer risk.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.Semantic proximity Read ↗

MTHFD1 G1958A, BHMT G742A, TC2 C776G and TC2 A67G polymorphisms and head and neck squamous cell carcinoma risk.Semantic proximity Read ↗

Head and neck cancer susceptibility: a genetic marker in the methylenetetrahydrofolate reductase gene.Semantic proximity Read ↗

Systematic review on the relationship between genetic polymorphisms of methylenetetrahydrofolate reductase and esophageal squamous cell carcinoma.Semantic proximity Read ↗

Polymorphisms in methylenetetrahydrofolate reductase and cystathionine beta-synthase in oral cancer - a case-control study in southeastern Brazilians.Semantic proximity Read ↗

MTHFR C677T gene polymorphism and head and neck cancer risk: a meta-analysis based on 23 publications.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.