Article
Polymorphism of methylenetetrahydrofolate reductase (MTHFR) gene and risk of head and neck squamous cell carcinoma.
Brazilian journal of otorhinolaryngology - 1 Jan 2000
Rodrigues Juliana Olsen, Galbiatti Ana Lívia Silva, Ruiz Mariangela Torreglosa, Raposo Luiz Sergio, Maniglia José Victor, Pavarino-Bertelli Erika Cristina, Goloni-Bertollo Eny Maria
Abstract excerpt
UNLABELLED: Methylenetetrahydrofolate reductase gene (MTHFR) C677T polymorphism may be a risk factor for head and neck squamous cell carcinoma due to changes in folate levels that can induce disorders in the methylation pathway, which results in carcinogenesis. AIM: To evaluate MTHFR C677T polymo...
Topics
- Age Factors
- Aged
- Carcinoma, Squamous Cell
- Female
- Genetic Predisposition to Disease
- Head and Neck Neoplasms
- Humans
- Logistic Models
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Odds Ratio
- Polymerase Chain Reaction
- Polymorphism, Genetic