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Article

Polymorphisms in methylenetetrahydrofolate reductase and cystathionine beta-synthase in oral cancer - a case-control study in southeastern Brazilians.

Brazilian journal of otorhinolaryngology - 1 Jan 2000

Barbosa Andressa, Dos Santos Marcelo, de Podestá José Roberto Vasconcelos, Gouvêa Sônia Alves, Von Zeidler Sandra Ventorin, Louro Iúri Drumond, Cordeiro-Silva Melissa de Freitas

Abstract excerpt

INTRODUCTION: Oral squamous cell carcinoma (OSCC) is a serious public health problem, due to its high mortality rate and worldwide rising incidence. OSCC susceptibility is mediated by interactions between genetic and environmental factors. Studies suggest that genetic variants encoding enzymes involved in folate metabolism may modulate OSCC risk by altering DNA synthesis/repair and methylation process. OBJECTIVE:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26749456
DOI: 10.1016/j.bjorl.2015.10.012
PMCID: PMC9444640

Genes

MTHFR
CBS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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