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Article

DNMT3B C46359T and SHMT1 C1420T polymorphisms in the folate pathway in carcinogenesis of head and neck.

Molecular biology reports - 1 Feb 2014

Succi Maysa, de Castro Tialfi Bergamin, Galbiatti Ana Lívia Silva, Arantes Lidia Maria Rebolho Batista, da Silva Jéssika Nunes Gomes, Maniglia José Victor, Raposo Luiz Sérgio, Pavarino Erika Cristina, Goloni-Bertollo Eny Maria

Abstract excerpt

Folate is an essential nutrient with important roles in the synthesis, repair, and DNA methylation. Polymorphisms in genes encoding enzymes involved in folate metabolism can change these processes and modulate cancer development. We investigated DNMT3B C46359T (rs2424913) and SHMT1 C1420T (rs1979277) polymorphisms related to folate pathway in head and neck cancer (HNC) risk and the association of the disease with...

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Source

Identifiers

PMID: 24362509
DOI: 10.1007/s11033-013-2895-6

Genes

SHMT1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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