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Article

Association study of the common polymorphisms in the folate-methionine pathway with retinoblastoma.

Ophthalmic genetics - 1 Dec 2016

Soleimani Elaheh, Saliminejad Kioomars, Akbari Mohammad Taghi, Kamali Koorosh, Ahani Ali

Abstract excerpt

BACKGROUND: Folate and methionine metabolism enzymes could affect DNA synthesis and repair, and their methylation and polymorphisms have been associated with some forms of cancer. This study was carried out to investigate whether the MTHFR C677T (rs1801133), MTHFR A1298C (rs1801131) and TYMS 2R/3R (rs34743033) polymorphisms are associated with susceptibility to retinoblastoma in an Iranian population. METHODS: A...

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Share to Folic Acid
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Source

Identifiers

PMID: 26914443
DOI: 10.3109/13816810.2015.1107596

Genes

MTHFR
TYMS

Variants

rs1801133
rs1801133

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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