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Article

Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms in oral squamous cell carcinoma in south-east Iran.

Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology - 1 Feb 2016

Miri-Moghaddam Ebrahim, Saravani Shirin, Garme Yasamn, Khosravi Arezoo, Bazi Ali, Motazedian Jamaledin

Abstract excerpt

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) gene encodes an essential enzyme involving in folate metabolism. Due to the role of folate in DNA integrity, polymorphisms of MTHFR are interesting targets for cancer risk studies. Our goal was to evaluate the prevalence of MTHFR C677T and A1298T single nucleotide polymorphisms in oral squamous cell carcinoma (OSCC). METHODS: The study was conducted on 57...

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PMID: 26218632
DOI: 10.1111/jop.12343

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MTHFR

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