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Article

Mendelian randomization provides no evidence for a causal role of serum urate in increasing serum triglyceride levels.

Circulation. Cardiovascular genetics - 1 Dec 2014

Rasheed Humaira, Hughes Kim, Flynn Tanya J, Merriman Tony R

Abstract excerpt

BACKGROUND: Triglycerides and their lipoprotein transport molecules are risk factors for heart disease. Observational studies have associated elevated levels of serum urate (SU) with triglycerides and risk of heart disease. However, owing to unmeasured confounding, observational studies do not provide insight into the causal relationship between SU and triglyceride. The aim of this study was to test for a causal...

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Identifiers

PMID: 25249548
DOI: 10.1161/CIRCGENETICS.114.000556
PMCID: PMC4270849

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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