Article
Uric Acid and Cardiovascular Events: A Mendelian Randomization Study.
Journal of the American Society of Nephrology : JASN - 1 Nov 2015
Kleber Marcus E, Delgado Graciela, Grammer Tanja B, Silbernagel Günther, Huang Jie, Krämer Bernhard K, Ritz Eberhard, März Winfried
Abstract excerpt
Obesity and diets rich in uric acid-raising components appear to account for the increased prevalence of hyperuricemia in Westernized populations. Prevalence rates of hypertension, diabetes mellitus, CKD, and cardiovascular disease are also increasing. We used Mendelian randomization to examine whether uric acid is an independent and causal cardiovascular risk factor. Serum uric acid was measured in 3315 patients...
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