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Article

Nicotine N-glucuronidation relative to N-oxidation and C-oxidation and UGT2B10 genotype in five ethnic/racial groups.

Carcinogenesis - 1 Nov 2014

Murphy Sharon E, Park Sung-Shim L, Thompson Elizabeth F, Wilkens Lynne R, Patel Yesha, Stram Daniel O, Le Marchand Loic

Abstract excerpt

Nicotine metabolism influences smoking behavior and differences in metabolism probably contribute to ethnic variability in lung cancer risk. We report here on the proportion of nicotine metabolism by cytochrome P450 2A6-catalyzed C-oxidation, UDP-glucuronosyl transferase 2B10 (UGT2B10)-catalyzed N-glucuronidation and flavin monooxygenase 3-catalyzed N-oxidation in five ethnic/racial groups and the role of UGT2B10...

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Identifiers

PMID: 25233931
DOI: 10.1093/carcin/bgu191
PMCID: PMC4216060

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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