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Article

Smoking behavior and related cancers: the role of CYP2A6 polymorphisms.

Current opinion in molecular therapeutics - 1 Dec 2007

Nakajima Miki

Abstract excerpt

Smoking exerts complex central and peripheral nervous system, behavioral, cardiovascular, and endocrine effects in humans and is a primary risk factor for various cancers. Nicotine, a major constituent of tobacco, is the compound that is responsible for the development and maintenance of tobacco dependence. The absorbed nicotine is rapidly and extensively metabolized to inactive cotinine by CYP2A6 in human...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18041664

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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