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Article

Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.

PLoS genetics - 1 Aug 2014

Tsutsui Yasuhiro, Kurokawa Yumiko, Ito Kentaro, Siddique Md Shahjahan P, Kawano Yumiko, Yamao Fumiaki, Iwasaki Hiroshi

Abstract excerpt

Fbh1, an F-box helicase related to bacterial UvrD, has been proposed to modulate homologous recombination in fission yeast. We provide several lines of evidence for such modulation. Fbh1, but not the related helicases Srs2 and Rqh1, suppressed the formation of crossover recombinants from single HO-induced DNA double-strand breaks. Purified Fbh1 in complex with Skp1 (Fbh1-Skp1 complex) inhibited Rad51-driven DNA...

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Identifiers

PMID: 25165823
DOI: 10.1371/journal.pgen.1004542
PMCID: PMC4148199

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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