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Article

Role for the fission yeast RecQ helicase in DNA repair in G2.

Molecular and cellular biology - 1 May 2003

Laursen Louise V, Ampatzidou Eleni, Andersen Anni H, Murray Johanne M

Abstract excerpt

Members of the RecQ helicase subfamily are mutated in several human genomic instability syndromes, such as Bloom, Werner, and Rothmund-Thomson syndromes. We show that Rqh1, the single Schizosaccharomyces pombe homologue, is a 3'-to-5' helicase and exists with Top3 in a high-molecular-weight complex. top3 deletion is inviable, and this is suppressed by concomitant loss of rqh1 helicase activity or loss of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12724426
DOI: 10.1128/MCB.23.10.3692-3705.2003
PMCID: PMC164774

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role for the fission yeast RecQ helicase in DNA repair in G2.PMID 12724426Read ↗

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