Article
Role of Blm and collaborating factors in recombination and survival following replication stress in Ustilago maydis.
DNA repair - 4 Jun 2009
Mao Ninghui, Kojic Milorad, Holloman William K
Abstract excerpt
Inactivation of the structural gene for the RecQ family member, BLM in human, Sgs1 in budding yeast, or Rqh1 in fission yeast leads to inappropriate recombination, chromosome abnormalities, and disturbed replication fork progression. Studies with yeasts have demonstrated that auxiliary gene functions can contribute in overlapping ways with Sgs1 or Rqh1 to circumvent or overcome lesions in DNA caused by certain...
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