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Article

Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates.

Molecular and cellular biology - 1 Sept 2005

Morishita Takashi, Furukawa Fumiko, Sakaguchi Chikako, Toda Takashi, Carr Antony M, Iwasaki Hiroshi, Shinagawa Hideo

Abstract excerpt

In an effort to identify novel genes involved in recombination repair, we isolated fission yeast Schizosaccharomyces pombe mutants sensitive to methyl methanesulfonate (MMS) and a synthetic lethal with rad2. A gene that complements such mutations was isolated from the S. pombe genomic library, and subsequent analysis identified it as the fbh1 gene encoding the F-box DNA helicase, which is conserved in mammals but...

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Identifiers

PMID: 16135799
DOI: 10.1128/MCB.25.18.8074-8083.2005
PMCID: PMC1234317

Genes

RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Role of the Schizosaccharomyces pombe F-Box DNA helicase in processing recombination intermediates.PMID 16135799Read ↗

The severe slow growth of Deltasrs2 Deltarqh1 in Schizosaccharomyces pombe is suppressed by loss of recombination and checkpoint genes.Semantic proximity Read ↗

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The F-Box DNA helicase Fbh1 prevents Rhp51-dependent recombination without mediator proteins.Semantic proximity Read ↗

Helicase activity is only partially required for Schizosaccharomyces pombe Rqh1p function.Semantic proximity Read ↗

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The N-terminal region of the Schizosaccharomyces pombe RecQ helicase, Rqh1p, physically interacts with Topoisomerase III and is required for Rqh1p function.Semantic proximity Read ↗

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