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Sfh1, an essential component of the RSC chromatin remodeling complex, maintains genome integrity in fission yeast.

Genes to cells : devoted to molecular & cellular mechanisms - 1 Sept 2018

Kotomura Naoe, Tsunemine Satoru, Kuragano Masahiro, Asanuma Takahiro, Nakagawa Hiromi, Tanaka Katsunori, Murakami Yota

Abstract excerpt

Abp1 is a fission yeast CENP-B homologue that contributes to centromere function, silencing at pericentromeric heterochromatin and silencing of retrotransposons. We identified the sfh1 gene, encoding a core subunit of the fission yeast chromatin remodeling complex RSC as an Abp1-interacting protein. Because sfh1 is essential for growth, we isolated temperature-sensitive sfh1 mutants. These mutants showed defects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30155942
DOI: 10.1111/gtc.12629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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