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Article

Association study of TPH2 polymorphisms and bipolar disorder in the Han Chinese population.

Progress in neuro-psychopharmacology & biological psychiatry - 2 Jan 2015

Chen Shiqing, Huang Xiaoye, Yu Tao, Li Xin, Cao Yanfei, Li Xingwang, Xu Fei, Yang Fengping, Jesse Forrest Fabian, Xu Mingqing, Li Weidong, He Lin, He Guang

Abstract excerpt

OBJECTIVE: Bipolar disorder (BPD) is a serious and common mental disorder with high heritability. The serotonergic system is known to be implicated in the etiology of the disorder. Tryptophan hydroxylase isoform-2 (TPH2), which controls the synthesis of serotonin in the brain, has been suggested as a candidate gene for BDP. The aim of this study was to examine the association between the polymorphisms in TPH2 and...

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Source

Identifiers

PMID: 25152196
DOI: 10.1016/j.pnpbp.2014.08.008

Genes

TPH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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