Article
Association study of tryptophan hydroxylase-2 gene in schizophrenia and its clinical features in Chinese Han population.
Journal of molecular neuroscience : MN - 1 Mar 2011
Zhang Chen, Li Zezhi, Shao Yang, Xie Bin, Du Yasong, Fang Yiru, Yu Shunying
Abstract excerpt
Schizophrenia is a chronic and severe mental illness which is characterized by the development of various detrimental clinical features, and its etiology still remains unknown. Based on the evidence from neurobiological and pharmacological research, dysfunctions in central serotonergic transmission may be involved in the development of schizophrenia. Tryptophan hydroxylase 2 (TPH2), a newly identified isoform of...
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