Article
Influence of TPH2 variants on diagnosis and response to treatment in patients with major depression, bipolar disorder and schizophrenia.
Psychiatry research - 30 Aug 2011
Serretti Alessandro, Chiesa Alberto, Porcelli Stefano, Han Changsu, Patkar Ashwin A, Lee Soo-Jung, Park Moon Ho, Pae Chi-Un
Abstract excerpt
The present study is aimed at exploring whether some single nucleotide polymorphisms (SNPs) within the tryptophan hydroxylase 2 gene (TPH2) could be associated with major depression (MD), bipolar disorder (BD) and schizophrenia and whether they could predict clinical outcomes in Korean in-patients treated with antidepressants, mood stabilizers and antipsychotics, respectively. One hundred forty-five patients with...
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