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Article

Mutational Status of CDKN2A and TP53 Genes in Laryngeal Squamous Cell Carcinoma.

Pathology oncology research : POR - 1 Apr 2015

Todorova Teodora A, Jordanov Stanislav H, Stancheva Gergana S, Chalakov Ivan J, Melnicharov Mincho B, Kunev Kuncho V, Mitev Vanio I, Kaneva Radka P, Goranova Teodora E

Abstract excerpt

Laryngeal squamous cell carcinoma (LSCC) is the second most common tumour of the head and neck. It is characterized by frequent aberrations in two cell-cycle regulators--CDKN2A and TP53. However, LSCC has been often studied as a part of the group of head and neck cancers and not as an individual entity. In the current study we aimed to examine mutation status of CDKN2A and TP53 genes in 108 LSCC patients. DNA was...

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PMID: 25149524
DOI: 10.1007/s12253-014-9836-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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