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Combined Effect of HPV and Several Gene SNPs in Laryngeal Cancer.

Medicina (Kaunas, Lithuania) - 17 Feb 2020

Stumbrytė-Kaminskienė Aušra, Gudlevičienė Živilė, Dabkevičienė Daiva, Mackevičienė Irina

Abstract excerpt

Background and objectives: Laryngeal squamous cell carcinoma (LSCC) is one of the most common head and neck tumors. The molecular mechanism of LSCC remains unclear. The aim of this study was to evaluate the prevalence of Human papillomavirus (HPV) and single nucleotide polymorphisms (SNPs) of TP53, MDM2, MDM4, MTHFR, CASP8, and CCR5 genes in LSCC, and to assess their correlations with patient survival. Materials...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32079256
DOI: 10.3390/medicina56020081
PMCID: PMC7074362

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