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Selected CDKN2A and MDM2 polymorphisms in oral cavity cancer.

Acta biochimica Polonica - 7 May 2020

Gaździcka Jadwiga, Gołąbek Karolina, Strzelczyk Joanna Katarzyna, Kiczmer Paweł, Miśkiewicz-Orczyk Katarzyna, Krakowczyk Łukasz, Ostrowska Zofia, Misiołek Maciej

Abstract excerpt

The head and neck squamous cell carcinoma (HNSCC) is an aggressive human malignancy diagnosed in more than 800 000 new cases worldwide, and mostly arises in the oral cavity, oropharynx, larynx, hypopharynx, and nasopharynx. The study presented here aimed to determine a possible association of rs11515 and rs3088440 gene polymorphisms in the CDKN2A gene (cyclin dependent kinase inhibitor 2A), as well as rs769412...

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PMID: 32379408
DOI: 10.18388/abp.2020_5195

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