Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tubular urate transporter gene polymorphisms differentiate patients with gout who have normal and decreased urinary uric acid excretion.

The Journal of rheumatology - 1 Sept 2014

Torres Rosa J, de Miguel Eugenio, Bailén Rebeca, Banegas José R, Puig Juan G

Abstract excerpt

OBJECTIVE: Primary gout has been associated with single-nucleotide polymorphisms (SNP) in several tubular urate transporter genes. No study has assessed the association of reabsorption and secretion urate transporter gene SNP with gout in a single cohort of documented primary patients with gout carefully subclassified as normoexcretors or underexcretors. METHODS: Three reabsorption SNP (SLC22A12/URAT1,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles
Share to ABCG2 gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperuricemia

Share to Organic Anion Transporters

Share to Polymorphism, Single Nucleotide

Share to Uric Acid

Source

Identifiers

PMID: 25128519
DOI: 10.3899/jrheum.140126

Genes

ABCG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tubular urate transporter gene polymorphisms differentiate patients with gout who have normal and decreased urinary uric acid excretion.PMID 25128519Read ↗

NPT1/SLC17A1 is a renal urate exporter in humans and its common gain-of-function variant decreases the risk of renal underexcretion gout.Semantic proximity Read ↗

A machine learning-assisted model for renal urate underexcretion with genetic and clinical variables among Chinese men with gout.Semantic proximity Read ↗

The Role of ABCG2 in the Pathogenesis of Primary Hyperuricemia and Gout-An Update.Semantic proximity Read ↗

A common variant of organic anion transporter 4 (OAT4/SLC22A11) gene is associated with renal underexcretion type gout.Semantic proximity Read ↗

Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes.Semantic proximity Read ↗

Common missense variant of monocarboxylate transporter 9 (MCT9/SLC16A9) gene is associated with renal overload gout, but not with all gout susceptibility.Semantic proximity Read ↗

ABCG2 dysfunction increases the risk of renal overload hyperuricemia.Semantic proximity Read ↗

GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes.Semantic proximity Read ↗

ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload.Semantic proximity Read ↗

Hyperuricemia Subtypes Classified According to Renal Uric Acid Handling Manifesting Distinct Phenotypic and Genetic Profiles in People With Gout.Semantic proximity Read ↗

Common defects of ABCG2, a high-capacity urate exporter, cause gout: a function-based genetic analysis in a Japanese population.Semantic proximity Read ↗

Control of renal uric acid excretion and gout.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.