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Article

Role of somatic cancer mutations in human protein lysine methyltransferases.

Biochimica et biophysica acta - 1 Dec 2014

Kudithipudi Srikanth, Jeltsch Albert

Abstract excerpt

Methylation of lysine residues is an important post-translational modification of histone and non-histone proteins, which is introduced by protein lysine methyltransferases (PKMTs). An increasing number of reports demonstrate that aberrant lysine methylation plays a central role in carcinogenesis that is often correlated with abnormal expression of PKMTs. Recent whole genome and whole transcriptome sequencing...

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Identifiers

PMID: 25123655
DOI: 10.1016/j.bbcan.2014.08.002

Genes

SETD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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